RBFOX1 COOPERATES WITH MBNL1 TO CONTROL SPLICING IN MUSCLE, INCLUDING EVENTS ALTERED IN MYOTONIC DYSTROPHY TYPE 1.

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.

With the goal of identifying splicing alterations in myotonic dystrophy 1 (DM1) tissues that may yield insights into targets or mechanisms, we have surveyed mis-splicing events in three systems using a RT-PCR screening Accessories and validation platform.First, a transgenic mouse model expressing CUG-repeats identified splicing alterations shared w

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Women’s work–family conflict and its consequences in commuter marriages: The moderating role of spouses’ family commitment in a dyad analysis

This study aims to explore the relationship between work-family conflict and its consequences on job, family, and marital satisfaction among stay-at-home wives of commuter couples by testing the moderating effect of commuters’ family Motor Armature Refacing Stick (parental, marital, and household) commitment.The phenomenon of commuter marriages i

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The impact of early detection and intervention on congenital heart defects in infants and children: a systematic review

Congenital heart disease (CHD) is the leading cause of mortality among congenital disabilities, affecting approximately 1% of live births.This review analyzes the critical role of early detection and intervention strategies in optimizing care for pediatric patients with CHD, utilizing a comprehensive literature search across scientific databases su

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